BDBM321078 8-((2-amino-1,1-dideutero-2,4-dimethylpentyl)oxy)-9-chloro-5-ethyl-4-methylbenzo[c][1,7]naphthyridin-6(5H)-one::US10174044, Example 12

SMILES CCn1c2c(C)nccc2c2cc(Cl)c(OCC(C)(N)CC(C)C)cc2c1=O

InChI Key InChIKey=YUSHSHYAUMAPRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321078   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321078(8-((2-amino-1,1-dideutero-2,4-dimethylpentyl)oxy)-...)
Affinity DataIC50:  30nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent