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BDBM321130 (S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-6H-isochromeno[3,4-c]pyridin-2-amine::US10174044, Example 61

SMILES: CC(C)C[C@](C)(N)COc1ccc-2c(COc3cnc(N)cc-23)c1Cl

InChI Key: InChIKey=JUXPRFDTJSOLCD-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321130   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens)
BDBM321130
PNG
((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-6...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc-2c(COc3cnc(N)cc-23)c1Cl
Show InChI InChI=1S/C19H24ClN3O2/c1-11(2)7-19(3,22)10-25-15-5-4-12-13-6-17(21)23-8-16(13)24-9-14(12)18(15)20/h4-6,8,11H,7,9-10,22H2,1-3H3,(H2,21,23)/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.410n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US10174044 (2019)

More data for this
Ligand-Target Pair