BDBM321262 N-[3-(benzylmethylamino)propyl]-4-trifluoromethylbenzamide::US10179761, Compound 3.1.5

SMILES CN(CCCNC(=O)c1ccc(cc1)C(F)(F)F)Cc1ccccc1

InChI Key InChIKey=HLNYWGVTKKMJCB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 321262   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321262(N-[3-(benzylmethylamino)propyl]-4-trifluoromethylb...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H](+)-pentazocine from S1R in human Jurkat cell membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321262(N-[3-(benzylmethylamino)propyl]-4-trifluoromethylb...)
Affinity DataKi:  1.40nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321262(N-[3-(benzylmethylamino)propyl]-4-trifluoromethylb...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321262(N-[3-(benzylmethylamino)propyl]-4-trifluoromethylb...)
Affinity DataKi:  98nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
In DepthDetails US Patent