BDBM321369 7-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10183009, Example 84

SMILES C\C=C\Cn1cc(-c2ccc3NC(=O)CC(C)Nc3c2)c2cc[nH]c2c1=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321369   

TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM321369(7-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...)
Affinity DataIC50:  1.90E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent