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BDBM321416 Ac-Arg-cyclo(Lys-His- D-Phe-Arg-Trp-Asp)- NH2::US10179804, Example 96

SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(O)=O

InChI Key: InChIKey=SFDONRROKYVFHZ-ZLCORKTQSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321416   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM321416
PNG
(Ac-Arg-cyclo(Lys-His- D-Phe-Arg-Trp-Asp)- NH2 | US...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(O)=O
Show InChI InChI=1S/C50H69N17O10/c1-28(68)61-34(16-9-19-57-49(51)52)42(70)62-35-15-7-8-18-56-41(69)24-40(48(76)77)67-46(74)38(22-30-25-59-33-14-6-5-13-32(30)33)65-44(72)36(17-10-20-58-50(53)54)63-45(73)37(21-29-11-3-2-4-12-29)64-47(75)39(66-43(35)71)23-31-26-55-27-60-31/h2-6,11-14,25-27,34-40,59H,7-10,15-24H2,1H3,(H,55,60)(H,56,69)(H,61,68)(H,62,70)(H,63,73)(H,64,75)(H,65,72)(H,66,71)(H,67,74)(H,76,77)(H4,51,52,57)(H4,53,54,58)/t34-,35-,36-,37+,38-,39-,40-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1n/an/an/an/an/an/an/an/a



Palatin Technologies, Inc.

US Patent


Assay Description
Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...


US Patent US10179804 (2019)

More data for this
Ligand-Target Pair