BDBM321433 (E)-4-(4-(3-(3-amino-1H-pyrazol-1-yl)azetidine-1-carbonyl)-3-chlorophenyl)-6-(but-2-en-1-yl)-2-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one::US10183009, Example 117

SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CC(C3)n3ccc(N)n3)c(Cl)c2)c2cc(C)[nH]c2c1=O

InChI Key InChIKey=ZXJTVJAZRVKOEI-ONEGZZNKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321433   

TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM321433((E)-4-(4-(3-(3-amino-1H-pyrazol-1-yl)azetidine-1-c...)
Affinity DataIC50:  5nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent