BDBM32144 8-quinolinamine::8-quinolylamine::AS-232::US10005735, Table 1.2::US9394254, 18::cid_11359::quinolin-8-amine
SMILES Nc1cccc2cccnc12
InChI Key InChIKey=WREVVZMUNPAPOV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 32144
Affinity DataKi: >2.00E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University
Curated by PubChem BioAssay
Emory University
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University
Curated by PubChem BioAssay
Emory University
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain H37Rv))
The University Of Denver And Regis University
US Patent
The University Of Denver And Regis University
US Patent
Affinity DataIC50: 7.90E+4nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair