BDBM321472 4-[5-(6-acetyl-2,6-diazaspiro[3.3]heptane-2-carbonyl)-2-methoxy-phenyl]-6-[(E)-but-2-enyl]-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 77

SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(=O)N1CC2(CN(C2)C(C)=O)C1

InChI Key InChIKey=WUFDLPAISLJPDC-SNAWJCMRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321472   

TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM321472(4-[5-(6-acetyl-2,6-diazaspiro[3.3]heptane-2-carbon...)
Affinity DataIC50:  900nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent