BDBM321551 US10183021, Compound I-162
SMILES C[C@H]1CCCN([C@@H]1C(O)=O)c1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1
InChI Key InChIKey=OREKZCCNTFVURN-QKKBWIMNSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 321551
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals
US Patent
Ironwood Pharmaceuticals
US Patent
Affinity DataEC50: <100nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair