BDBM321622 US10183021, Compound I-397

SMILES OC1(CNc2nc(ncc2F)-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)CCOCC1

InChI Key InChIKey=CUUWZWXDJZUATK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321622   

TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals

US Patent
LigandPNGBDBM321622(US10183021, Compound I-397)
Affinity DataEC50: <100nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent