BDBM321899 (E)-Ethyl 1-((1-(3-(4-chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)acryloyl)-4-hydroxypiperidin-4-yl)methyl)-1H-pyrazole-4-carboxylate::US10183025, Example 32::US9763957, Example 32

SMILES CCOC(=O)c1cnn(CC2(O)CCN(CC2)C(=O)\C=C\c2ccc(Cl)cc2Cn2nnc(C)n2)c1

InChI Key InChIKey=DEUHQTQIQDMBLZ-FNORWQNLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 321899   

TargetAtaxin-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM321899((E)-Ethyl 1-((1-(3-(4-chloro-2-((5-methyl-2H-tetra...)
Affinity DataIC50:  3.5nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM321899((E)-Ethyl 1-((1-(3-(4-chloro-2-((5-methyl-2H-tetra...)
Affinity DataIC50:  3.5nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent