BDBM322003 (E)-3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)-1-(4-((3-methylisoxazol-5-yl)methyl)piperazin-1-yl)prop-2-en-1-one::US10183025, Example 101::US9763957, Example 101

SMILES Cc1cc(CN2CCN(CC2)C(=O)\C=C\c2ccc(cc2Cn2nnc(C)n2)C(F)(F)F)on1

InChI Key InChIKey=YMGXHCWFVGHETM-GQCTYLIASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322003   

TargetAtaxin-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM322003((E)-3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)-4-(tr...)
Affinity DataIC50:  5nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM322003((E)-3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)-4-(tr...)
Affinity DataIC50:  5nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent