BDBM322062 (E)-3-((2-(4-(3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)acryloyl)morpholin-2-yl)ethyl)amino)-4-ethoxycyclobut-3-ene-1,2-dione::US10183025, Example 150::US9763957, Example 150

SMILES CCOc1c(NCCC2CN(CCO2)C(=O)\C=C\c2ccc(Cl)cc2Cn2nnc(C)n2)c(=O)c1=O

InChI Key InChIKey=RLSTTXJLQBGZSW-FNORWQNLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322062   

TargetAtaxin-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM322062((E)-3-((2-(4-(3-(4-Chloro-2-((5-methyl-2H-tetrazol...)
Affinity DataIC50:  6.90nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM322062((E)-3-((2-(4-(3-(4-Chloro-2-((5-methyl-2H-tetrazol...)
Affinity DataIC50:  6.90nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent