BDBM322121 US10183913, Example 434::US11312688, Example 434

SMILES CNCc1cc(OCc2cc(Cl)ccc2F)n(CC2(CCCCC2)OC)n1

InChI Key InChIKey=PAJFRUWRZJZCIC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 322121   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322121(US10183913, Example 434 | US11312688, Example 434)
Affinity DataKi:  4.5nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322121(US10183913, Example 434 | US11312688, Example 434)
Affinity DataKi:  4.5nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322121(US10183913, Example 434 | US11312688, Example 434)
Affinity DataKi:  8.10nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322121(US10183913, Example 434 | US11312688, Example 434)
Affinity DataKi:  8.10nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent