BDBM322140 US10183917, Example 4
SMILES OC(=O)c1ccc2CCc3cc(OCc4c(onc4-c4c(Cl)cccc4Cl)C4CC4)ncc3Oc2c1
InChI Key InChIKey=CDJOMZYNYHOFGM-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 322140
Affinity DataEC50: 46nMAssay Description:Purchasing invitrogen PV4833 kits.First, the required amount of the compound was weighed and dissolved in 100% DMSO at the maximum concentration of 3...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at FXR-LBD (unknown origin) assessed as induction of coactivator SRC-1 peptide recruitment measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 161nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells by luciferase reporter assayMore data for this Ligand-Target Pair