BDBM322607 3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl- morpholin-2- yl]methoxy}-N- {(1R)-1-[6- (trifluoromethyl) pyridazin-3- yl]ethyl} benzamide::US10183937, Example 418::US10202369, Example 418::US10472354, Example 418

SMILES CCc1cnc(s1)-c1cc(OC[C@@H]2CN(C)CCO2)cc(c1)C(=O)N[C@H](C)c1ccc(nn1)C(F)(F)F

InChI Key InChIKey=SIFMRPZFMXLARV-BEFAXECRSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 322607   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM322607(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl-...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM322607(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl-...)
Affinity DataIC50:  1.56E+3nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM322607(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl-...)
Affinity DataIC50:  1.56E+3nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM322607(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl-...)
Affinity DataIC50:  1.56E+3nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM322607(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl-...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM322607(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methyl-...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent