BDBM32266 2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carboxamide::MLS000094619::N-[2-(3,4-dimethoxyphenyl)ethyl]-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide::N-[2-(3,4-dimethoxyphenyl)ethyl]-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide::N-[2-(3,4-dimethoxyphenyl)ethyl]-2,3-di-2-furylquinoxaline-6-carboxamide::SMR000030172::cid_3238500

SMILES COc1ccc(CCNC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1OC

InChI Key InChIKey=RUFKJJVQXFMXGP-UHFFFAOYSA-N

Data  1 IC50  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 32266   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  2.07E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  4.30E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  5.24E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  1.22E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  1.36E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  1.49E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  2.58E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  1.54E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  2.08E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataEC50:  1.84E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32266(2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carb...)
Affinity DataIC50:  4.65E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay