BDBM322981 5-tert-butyl-7-(2-methylpyrazol-3-yl)-3-[(2-methylsulfonylphenyl)methyl]triazolo[4,5-d]pyrimidine::US10183946, Example 12

SMILES Cn1nccc1-c1nc(nc2n(Cc3ccccc3S(C)(=O)=O)nnc12)C(C)(C)C

InChI Key InChIKey=BTRPRPFQQADLJE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322981   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM322981(5-tert-butyl-7-(2-methylpyrazol-3-yl)-3-[(2-methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM322981(5-tert-butyl-7-(2-methylpyrazol-3-yl)-3-[(2-methyl...)
Affinity DataEC50:  3nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent