BDBM323066 (1R,2R and 1S,1S)-N-(4-Cyano-3-methyl- 1,2-thiazol-5-yl)-2-[4-(1H-pyrazol-5- yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 49::US10508119, Example 49

SMILES Cc1nsc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2ccn[nH]2)c1C#N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323066   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM323066((1R,2R and 1S,1S)-N-(4-Cyano-3-methyl- 1,2-thiazol...)
Affinity DataIC50:  44nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent