BDBM323132 2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)-4-((trans-4-(2,4,5-trifluorophenyl)piperidin-3-yl)methoxy)benzenesulfonamide::US9630929, Example 106

SMILES Fc1cc(F)c(cc1F)C1CCNC[C@H]1COc1cc(F)c(cc1F)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=CXZDUWKESZWTPN-VUWPPUDQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323132   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323132(2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)-4-((trans-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323132(2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)-4-((trans-4...)
Affinity DataIC50:  181nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent