BDBM323229 US10189859, Compound 103

SMILES COCCOCCOCCN1CCN(CC1)c1nnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=IKCMRKOHUDOPPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323229   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM323229(US10189859, Compound 103)
Affinity DataIC50: >2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM323229(US10189859, Compound 103)
Affinity DataIC50: <5.00E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM323229(US10189859, Compound 103)
Affinity DataIC50: >2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM323229(US10189859, Compound 103)
Affinity DataIC50:  5.49E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent