BDBM323599 (E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)-2-methylhex-2-enoic acid ::US10188627, Compound 8k

SMILES CN(Cc1ccccc1OCCC\C=C(/C)C(O)=O)C(=O)c1ccc(cc1)-c1ccco1

InChI Key InChIKey=UOUIWYBSJFMAKV-UFWORHAWSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 323599   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323599((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)
Affinity DataEC50:  1.85E+3nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPPAR delta protein(Rattus norvegicus (Rat))
Mitobridge

US Patent
LigandPNGBDBM323599((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)
Affinity DataEC50:  1.85E+3nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Mitobridge

Curated by ChEMBL
LigandPNGBDBM323599((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human PPARalpha LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323599((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)
Affinity DataEC50:  1.85E+3nMAssay Description:Activation of human PPARdelta LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Mitobridge

Curated by ChEMBL
LigandPNGBDBM323599((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human PPARgamma LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323599((E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of yeast GAL4 DNA binding domain-fused PPARdelta LBD (unknown origin) expressed in CV-1 cells after 24 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed