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BDBM323603 Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)-2-methylhexanoic acid ::US10188627, Compound 8o

SMILES: CC(CCCCOc1ccccc1CN(C)C(=O)c1ccc(cc1)-c1ccco1)C(O)=O

InChI Key: InChIKey=HASKDUVBSFNKIR-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 323603   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM323603
PNG
(Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzami...)
Show SMILES CC(CCCCOc1ccccc1CN(C)C(=O)c1ccc(cc1)-c1ccco1)C(O)=O
Show InChI InChI=1S/C26H29NO5/c1-19(26(29)30)8-5-6-16-31-24-10-4-3-9-22(24)18-27(2)25(28)21-14-12-20(13-15-21)23-11-7-17-32-23/h3-4,7,9-15,17,19H,5-6,8,16,18H2,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 229n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...


US Patent US10188627 (2019)


Article DOI: 10.1016/j.bmcl.2005.03.055
BindingDB Entry DOI: 10.7270/Q2HX1FR6
More data for this
Ligand-Target Pair
PPAR delta protein


(Rattus norvegicus (Rat))
BDBM323603
PNG
(Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzami...)
Show SMILES CC(CCCCOc1ccccc1CN(C)C(=O)c1ccc(cc1)-c1ccco1)C(O)=O
Show InChI InChI=1S/C26H29NO5/c1-19(26(29)30)8-5-6-16-31-24-10-4-3-9-22(24)18-27(2)25(28)21-14-12-20(13-15-21)23-11-7-17-32-23/h3-4,7,9-15,17,19H,5-6,8,16,18H2,1-2H3,(H,29,30)
PDB

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 229n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...


US Patent US10188627 (2019)


Article DOI: 10.1016/j.bmcl.2005.03.055
BindingDB Entry DOI: 10.7270/Q2HX1FR6
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM323603
PNG
(Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzami...)
Show SMILES CC(CCCCOc1ccccc1CN(C)C(=O)c1ccc(cc1)-c1ccco1)C(O)=O
Show InChI InChI=1S/C26H29NO5/c1-19(26(29)30)8-5-6-16-31-24-10-4-3-9-22(24)18-27(2)25(28)21-14-12-20(13-15-21)23-11-7-17-32-23/h3-4,7,9-15,17,19H,5-6,8,16,18H2,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 1.64E+3n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...


US Patent US10188627 (2019)


Article DOI: 10.1016/j.bmcl.2005.03.055
BindingDB Entry DOI: 10.7270/Q2HX1FR6
More data for this
Ligand-Target Pair