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BDBM323607 Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)-2,2-dimethylhexanoic acid ::US10188627, Compound 8s

SMILES: CN(Cc1ccccc1OCCCCC(C)(C)C(O)=O)C(=O)c1ccc(cc1)-c1ccco1

InChI Key: InChIKey=RDTZXAYSBVNVKN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323607   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PPAR delta protein


(Rattus norvegicus (Rat))
BDBM323607
PNG
(Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzami...)
Show SMILES CN(Cc1ccccc1OCCCCC(C)(C)C(O)=O)C(=O)c1ccc(cc1)-c1ccco1
Show InChI InChI=1S/C27H31NO5/c1-27(2,26(30)31)16-6-7-17-32-24-10-5-4-9-22(24)19-28(3)25(29)21-14-12-20(13-15-21)23-11-8-18-33-23/h4-5,8-15,18H,6-7,16-17,19H2,1-3H3,(H,30,31)
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 511n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...


US Patent US10188627 (2019)

More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM323607
PNG
(Synthesis of 6-(2-((4-(furan-2-yl)-N-methylbenzami...)
Show SMILES CN(Cc1ccccc1OCCCCC(C)(C)C(O)=O)C(=O)c1ccc(cc1)-c1ccco1
Show InChI InChI=1S/C27H31NO5/c1-27(2,26(30)31)16-6-7-17-32-24-10-5-4-9-22(24)19-28(3)25(29)21-14-12-20(13-15-21)23-11-8-18-33-23/h4-5,8-15,18H,6-7,16-17,19H2,1-3H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 511n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...


US Patent US10188627 (2019)

More data for this
Ligand-Target Pair