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BDBM323610 (1R*,2R*)-2-(3-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)propyl) cyclopropane-1-carboxylic acid::US10188627, Compound 8v

SMILES: CN(Cc1ccccc1OCCC[C@@H]1CC1C(O)=O)C(=O)c1ccc(cc1)-c1ccco1

InChI Key: InChIKey=SCHIHSWLJKKKDG-PSDZMVHGSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323610   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM323610
PNG
( (1R*,2R*)-2-(3-(2-((4-(furan-2-yl)-N-methylbenzam...)
Show SMILES CN(Cc1ccccc1OCCC[C@@H]1CC1C(O)=O)C(=O)c1ccc(cc1)-c1ccco1
Show InChI InChI=1S/C26H27NO5/c1-27(25(28)19-12-10-18(11-13-19)23-9-5-15-31-23)17-21-6-2-3-8-24(21)32-14-4-7-20-16-22(20)26(29)30/h2-3,5-6,8-13,15,20,22H,4,7,14,16-17H2,1H3,(H,29,30)/t20-,22?/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.51E+3n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...


US Patent US10188627 (2019)

More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM323610
PNG
( (1R*,2R*)-2-(3-(2-((4-(furan-2-yl)-N-methylbenzam...)
Show SMILES CN(Cc1ccccc1OCCC[C@@H]1CC1C(O)=O)C(=O)c1ccc(cc1)-c1ccco1
Show InChI InChI=1S/C26H27NO5/c1-27(25(28)19-12-10-18(11-13-19)23-9-5-15-31-23)17-21-6-2-3-8-24(21)32-14-4-7-20-16-22(20)26(29)30/h2-3,5-6,8-13,15,20,22H,4,7,14,16-17H2,1H3,(H,29,30)/t20-,22?/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 210n/an/an/an/a



Mitobridge, Inc.; Salk Institute for Biological Studies

US Patent


Assay Description
Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...


US Patent US10188627 (2019)

More data for this
Ligand-Target Pair