BDBM323610 (1R*,2R*)-2-(3-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)propyl) cyclopropane-1-carboxylic acid::US10188627, Compound 8v
SMILES: CN(Cc1ccccc1OCCC[C@@H]1CC1C(O)=O)C(=O)c1ccc(cc1)-c1ccco1
InChI Key: InChIKey=SCHIHSWLJKKKDG-PSDZMVHGSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM323610![]() ( (1R*,2R*)-2-(3-(2-((4-(furan-2-yl)-N-methylbenzam...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.; Salk Institute for Biological Studies US Patent | Assay Description Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2... | US Patent US10188627 (2019) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM323610![]() ( (1R*,2R*)-2-(3-(2-((4-(furan-2-yl)-N-methylbenzam...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Mitobridge, Inc.; Salk Institute for Biological Studies US Patent | Assay Description Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif... | US Patent US10188627 (2019) | |||||||||||
More data for this Ligand-Target Pair |