BDBM323618 US10188627, Comparator Cmpd. 2

SMILES OC(=O)CCCCCOc1ccccc1CN(C1CC1)C(=O)c1ccc(cc1)-c1ccco1

InChI Key InChIKey=CQKNIDGIDMCYLZ-UHFFFAOYSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323618   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323618(US10188627, Comparator Cmpd. 2)
Affinity DataEC50:  4.81nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323618(US10188627, Comparator Cmpd. 2)
Affinity DataEC50:  20nMAssay Description:Transactivation of N-terminal His-tagged human PPARdelta-LBD expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323618(US10188627, Comparator Cmpd. 2)
Affinity DataEC50:  20nMAssay Description:Agonist activity at N-terminal His-tagged human PPARdelta-LBD expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM323618(US10188627, Comparator Cmpd. 2)
Affinity DataEC50:  9.80nMAssay Description:Activation of human PPARdelta LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB