BDBM323810 US10189809, Compound I-33

SMILES Fc1ccccc1Cn1nc(cc1-c1nccs1)-c1ncccn1

InChI Key InChIKey=KSMQXTATHZCWEK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323810   

TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals

US Patent
LigandPNGBDBM323810(US10189809, Compound I-33)
Affinity DataEC50:  3.00E+4nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent