BDBM32387 phenyl-substituted sulfonamides, 6d

SMILES Nc1ccc(cc1)S(=O)(=O)N(CCNCCN(Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1)Cc1ccccc1

InChI Key InChIKey=LGNWJMPLPCSVBL-UHFFFAOYSA-N

Data  4 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32387   

TargetPepsin A(Porcine)
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataKi:  3.90E+3nM ΔG°:  -7.37kcal/moleT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataKi:  4.20E+3nM ΔG°:  -7.28kcal/molepH: 4.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin IV(Plasmodium falciparum)
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataKi:  7.50E+3nM ΔG°:  -6.94kcal/molepH: 4.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataKi:  9.60E+3nM ΔG°:  -6.79kcal/molepH: 5.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataIC50: >2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1 [22-457](Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataIC50: >2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed