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BDBM32422 Benzo[c][2,7]naphthyridine, 9

SMILES: COCCOc1cc2ncc3c(N)nc(cc3c2cc1OC)-n1ccnc1

InChI Key: InChIKey=QSSGYSRUMIOURP-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32422   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1)


(Homo sapiens (Human))
BDBM32422
PNG
(Benzo[c][2,7]naphthyridine, 9)
Show SMILES COCCOc1cc2ncc3c(N)nc(cc3c2cc1OC)-n1ccnc1
Show InChI InChI=1S/C19H19N5O3/c1-25-5-6-27-17-9-15-13(7-16(17)26-2)12-8-18(24-4-3-21-11-24)23-19(20)14(12)10-22-15/h3-4,7-11H,5-6H2,1-2H3,(H2,20,23)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 70n/an/an/an/a7.423



Wyeth Research



Assay Description
A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...


Bioorg Med Chem Lett 19: 5225-8 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)