BDBM324331 5-(tert-butyl)-N-(2- methyl-8-(2-((1-methyl- 1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-2,3,4,5-tetrahydro- 1H-benzo[c]azepin- 5-yl)- 1,3,4-oxadiazole-2- carboxamide::US10189829, Compound 99::US10961237, Compound 99::US11858926, Compound 99

SMILES CN1CCC(NC(=O)c2nnc(o2)C(C)(C)C)c2ccc(cc2C1)-c1ccnc(Nc2cnn(C)c2)n1

InChI Key InChIKey=ZZIUXMOUHPUXEK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 324331   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324331(5-(tert-butyl)-N-(2- methyl-8-(2-((1-methyl- 1H-py...)
Affinity DataIC50: <1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [14-552](Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324331(5-(tert-butyl)-N-(2- methyl-8-(2-((1-methyl- 1H-py...)
Affinity DataIC50: <1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324331(5-(tert-butyl)-N-(2- methyl-8-(2-((1-methyl- 1H-py...)
Affinity DataIC50: <1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent