BDBM324361 1-(tert-butyl)-N-(3-(2- hydroxyethyl)-7-(2-((1- methyl-1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-2,3,4,5-tetrahydro- 1H-benzo[d]azepin-1- yl)-1H-1,2,3-triazole-4- carboxamide::US10189829, Compound 53::US10227341, Compound 53::US10961237, Compound 53::US11858926, Compound 53

SMILES Cn1cc(Nc2nccc(n2)-c2ccc3C(CN(CCO)CCc3c2)NC(=O)c2cn(nn2)C(C)(C)C)cn1

InChI Key InChIKey=STBCYOWRYPXSMY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 324361   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324361(1-(tert-butyl)-N-(3-(2- hydroxyethyl)-7-(2-((1- me...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [14-552](Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324361(1-(tert-butyl)-N-(3-(2- hydroxyethyl)-7-(2-((1- me...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324361(1-(tert-butyl)-N-(3-(2- hydroxyethyl)-7-(2-((1- me...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324361(1-(tert-butyl)-N-(3-(2- hydroxyethyl)-7-(2-((1- me...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent