BDBM324363 N-(2-methyl-8-(2-((1- methyl-1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-2,3,4,5-tetrahydro- 1H-benzo[c]azepin-5-yl)- 5-(1,1,1-trifluoro-2- methylpropan-2-yl)- 1,3,4-oxadiazole-2- carboxamide::US10189829, Compound 57::US10227341, Compound 57::US10961237, Compound 57::US11858926, Compound 57

SMILES CN1CCC(NC(=O)c2nnc(o2)C(C)(C)C(F)(F)F)c2ccc(cc2C1)-c1ccnc(Nc2cnn(C)c2)n1

InChI Key InChIKey=CKPDQOCZFALKEL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 324363   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324363(N-(2-methyl-8-(2-((1- methyl-1H-pyrazol-4- yl)amin...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [14-552](Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324363(N-(2-methyl-8-(2-((1- methyl-1H-pyrazol-4- yl)amin...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324363(N-(2-methyl-8-(2-((1- methyl-1H-pyrazol-4- yl)amin...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324363(N-(2-methyl-8-(2-((1- methyl-1H-pyrazol-4- yl)amin...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent