BDBM324370 1-cyclobutyl-N-(8-(2- ((1-methyl-1H-pyrazol- 4-yl)amino)pyrimidin- 4-yl)-2-(oxetan-3-yl)- 2,3,4,5-tetrahydro-1H- benzo[c]azepin-5-yl)- 1H-1,2,3-triazole-4- carboxamide::US10189829, Compound 66::US10227341, Compound 66::US11858926, Compound 66

SMILES Cn1cc(Nc2nccc(n2)-c2ccc3C(CCN(Cc3c2)C2COC2)NC(=O)c2cn(nn2)C2CCC2)cn1

InChI Key InChIKey=RLRYTVUORICEOL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 324370   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324370(1-cyclobutyl-N-(8-(2- ((1-methyl-1H-pyrazol- 4-yl)...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [14-552](Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324370(1-cyclobutyl-N-(8-(2- ((1-methyl-1H-pyrazol- 4-yl)...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM324370(1-cyclobutyl-N-(8-(2- ((1-methyl-1H-pyrazol- 4-yl)...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent