BDBM324719 1'-({5-Chloro-1-[3-(piperazin-1- ylsulfonyl)propyl]-1H-indol-2- yl}methyl)spiro[cyclopropane-1,3'- pyrrolo[2,3-c]pyridin]-2'(1'H)-one::US10189838, Example 24-2

SMILES Clc1ccc2n(CCCS(=O)(=O)N3CCNCC3)c(CN3C(=O)C4(CC4)c4ccncc34)cc2c1

InChI Key InChIKey=RYGAKOJEQMMKEM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324719   

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324719(1'-({5-Chloro-1-[3-(piperazin-1- ylsulfonyl)propyl...)
Affinity DataEC50:  15nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent