BDBM32473 piperazine amide, 4t

SMILES Brc1ccc(o1)C(=O)Nc1cccc(-c2ccccc2)c1N1CCN(CC=C)CC1

InChI Key InChIKey=BHRVONRAOWCXOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32473   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32473(piperazine amide, 4t)
Affinity DataIC50: >2.00E+4nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32473(piperazine amide, 4t)
Affinity DataIC50: >2.00E+4nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed