BDBM32491 aryl piperidine, 9g

SMILES Cc1ccc(o1)C(=O)Nc1cccc(C)c1N1CCC2(CC1)OCCO2

InChI Key InChIKey=BHMYLUVZDOIZTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32491   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32491(aryl piperidine, 9g)
Affinity DataIC50:  330nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32491(aryl piperidine, 9g)
Affinity DataIC50:  530nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed