BDBM325438 (R)-1-(methylamino)-3- (4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)pyrazolo[1,5- a]pyrazin-6-yl)-1H- pyrazol-1-yl)propan-2-ol::US10189845, Example 100::US10730880, Example 100::US11028093, Example 100
SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@H](O)CNC)c1
InChI Key InChIKey=PMNFGEHMTFKKPU-GOSISDBHSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 325438
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair