BDBM32574 arylsulfonylpiperazine, 46

SMILES C[C@H]1CN(CCN1S(=O)(=O)c1ccc(cc1)C(C)(C)C)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=SOFGQQQVQZQJFS-INIZCTEOSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32574   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Amgen

LigandPNGBDBM32574(arylsulfonylpiperazine, 46)
Affinity DataIC50:  37nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32574(arylsulfonylpiperazine, 46)
Affinity DataIC50:  29nM EC50:  527nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair