BDBM326292 6-(1-benzofuran-5-yl)- 4-{[(1R)-1- cyclobutylethyl]amino}- 5-[4- (trifluoromethyl)benzyl]- 5H-pyrrolo[3,2- d]pyrimidine-2- carboxylic acid::US9637493, 1.6
SMILES C[C@@H](Nc1nc(nc2cc(-c3ccc4occc4c3)n(Cc3ccc(cc3)C(F)(F)F)c12)C(O)=O)C1CCC1
InChI Key InChIKey=YXSGUEZTKKJGQA-MRXNPFEDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 326292
Affinity DataIC50: 105nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM...More data for this Ligand-Target Pair