BDBM326298 5-[2-amino-4- (trifluoromethyl) benzyl]-4-{[(1R)-1- cyclobutylethyl] amino}-6-(3- methylphenyl)-5H- pyrrolo[3,2- d]pyrimidine-2- carboxylic acid::US9637493, 2.1
SMILES C[C@@H](Nc1nc(nc2cc(-c3cccc(C)c3)n(Cc3ccc(cc3N)C(F)(F)F)c12)C(O)=O)C1CCC1
InChI Key InChIKey=VYAHCRMFIULLEO-MRXNPFEDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 326298
Affinity DataIC50: 11nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM...More data for this Ligand-Target Pair