BDBM326316 5-{4-(5-chloropyridin-3- yl)-5-[(trans-4- methylcyclohexyl)methyl]- 5H-pyrrolo[3,2- d]pyrimidin-2-yl}-1,3,4- oxadiazol-2(3H)-one::US9637493, 4.5
SMILES C[C@H]1CC[C@H](Cn2ccc3nc(nc(-c4cncc(Cl)c4)c23)-c2n[nH]c(=O)o2)CC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 326316
Affinity DataIC50: 95nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM...More data for this Ligand-Target Pair