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BDBM32639 amino-oxazole, 2

SMILES: Nc1ncc(o1)C(=O)c1cccc(Br)c1

InChI Key: InChIKey=YDCMMVTWXORJGO-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32639   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Biotin Carboxylase


(Escherichia coli (strain K12))
BDBM32639
PNG
(amino-oxazole, 2)
Show SMILES Nc1ncc(o1)C(=O)c1cccc(Br)c1
Show InChI InChI=1S/C10H7BrN2O2/c11-7-3-1-2-6(4-7)9(14)8-5-13-10(12)15-8/h1-5H,(H2,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
DrugBank
MMDB
PDB
Article
PubMed
n/an/a 2.15E+4n/an/an/an/a8.023



Pfizer



Assay Description
Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...


ACS Chem Biol 4: 473-83 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)