BDBM327172 1-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin-3-yl)- benzyl]-piperidine-4-carboxylic acid (2-hydroxy-2-methyl-propyl)- amide::US9662339, 255

SMILES CC(C)(O)CNC(=O)C1CCN(Cc2ccc(cc2)[C@H]2COc3cccnc3O2)CC1

InChI Key InChIKey=BMARJSPDNJUQAS-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327172   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327172(1-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin...)
Affinity DataIC50:  0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent