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BDBM327236 4-chloro-N-{5-chloro-2-[(3-hydroxycyclopentyl)sulfonyl]phenyl}-3-(trifluoromethyl)benzenesulfonamide::US9663460, Example 25

SMILES: OC1CCC(C1)S(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key: InChIKey=AJJITZLILJWIRB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327236   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327236
PNG
(4-chloro-N-{5-chloro-2-[(3-hydroxycyclopentyl)sulf...)
Show SMILES OC1CCC(C1)S(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H16Cl2F3NO5S2/c19-10-1-6-17(30(26,27)12-3-2-11(25)8-12)16(7-10)24-31(28,29)13-4-5-15(20)14(9-13)18(21,22)23/h1,4-7,9,11-12,24-25H,2-3,8H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 76n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair