BindingDB logo
myBDB logout

BDBM327268 4-chloro-N-[5-chloro-2-(methylthio)phenyl]-2-fluorobenzenesulfonamide::US9663460, Example 58

SMILES: CSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1F

InChI Key: InChIKey=DXADQVXAYIIMFS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327268   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327268
PNG
(4-chloro-N-[5-chloro-2-(methylthio)phenyl]-2-fluor...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1F
Show InChI InChI=1S/C13H10Cl2FNO2S2/c1-20-12-4-2-9(15)7-11(12)17-21(18,19)13-5-3-8(14)6-10(13)16/h2-7,17H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 25n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair