BindingDB logo
myBDB logout

BDBM327306 N-{5-chloro-2-[(1H-pyrazol-3-ylmethyl)thio]phenyl}-1-benzofuran-2-sulfonamide::US9663460, Example 106

SMILES: Clc1ccc(SCc2cc[nH]n2)c(NS(=O)(=O)c2cc3ccccc3o2)c1

InChI Key: InChIKey=WZKUFKZMNKLPND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327306   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327306
PNG
(N-{5-chloro-2-[(1H-pyrazol-3-ylmethyl)thio]phenyl}...)
Show SMILES Clc1ccc(SCc2cc[nH]n2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H14ClN3O3S2/c19-13-5-6-17(26-11-14-7-8-20-21-14)15(10-13)22-27(23,24)18-9-12-3-1-2-4-16(12)25-18/h1-10,22H,11H2,(H,20,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 16n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair