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BDBM327326 N-{5-chloro-2-[(pyridin-3-ylmethyl)sulfinyl]phenyl}-1-benzofuran-2-sulfonamide::US9663460, Example 130

SMILES: Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1cccnc1

InChI Key: InChIKey=VPZJQHXNTCPASD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327326   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327326
PNG
(N-{5-chloro-2-[(pyridin-3-ylmethyl)sulfinyl]phenyl...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1cccnc1
Show InChI InChI=1S/C20H15ClN2O4S2/c21-16-7-8-19(28(24)13-14-4-3-9-22-12-14)17(11-16)23-29(25,26)20-10-15-5-1-2-6-18(15)27-20/h1-12,23H,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 76n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair