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BDBM327357 N-(2-{[(5-amino-4H-1,2,4-triazol-3-yl)methyl]thio}-5-chlorophenyl)-1-benzofuran-2-sulfonamide::US9663460, Example 163

SMILES: Nc1nnc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)[nH]1

InChI Key: InChIKey=QRKAWRCNYRXSFB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327357
PNG
(N-(2-{[(5-amino-4H-1,2,4-triazol-3-yl)methyl]thio}...)
Show SMILES Nc1nnc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)[nH]1
Show InChI InChI=1S/C17H14ClN5O3S2/c18-11-5-6-14(27-9-15-20-17(19)22-21-15)12(8-11)23-28(24,25)16-7-10-3-1-2-4-13(10)26-16/h1-8,23H,9H2,(H3,19,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair