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BDBM327374 N-(5-chloro-2-{[(2-fluoropyridin-3-yl)methyl]-sulfonyl}phenyl)-1-benzofuran-2-sulfonamide::US9663460, Example 181

SMILES: Fc1ncccc1CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1

InChI Key: InChIKey=HOJFNIBQSLBEEM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327374   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327374
PNG
(N-(5-chloro-2-{[(2-fluoropyridin-3-yl)methyl]-sulf...)
Show SMILES Fc1ncccc1CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C20H14ClFN2O5S2/c21-15-7-8-18(30(25,26)12-14-5-3-9-23-20(14)22)16(11-15)24-31(27,28)19-10-13-4-1-2-6-17(13)29-19/h1-11,24H,12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 79n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair