BindingDB logo
myBDB logout

BDBM327421 N-[2-(benzylsulfinyl)-5-cyanophenyl]-1-benzofuran-2-sulfonamide::US9663460, Example 228

SMILES: O=S(Cc1ccccc1)c1ccc(cc1NS(=O)(=O)c1cc2ccccc2o1)C#N

InChI Key: InChIKey=XLFXHENFOHZARF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327421   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327421
PNG
(N-[2-(benzylsulfinyl)-5-cyanophenyl]-1-benzofuran-...)
Show SMILES O=S(Cc1ccccc1)c1ccc(cc1NS(=O)(=O)c1cc2ccccc2o1)C#N
Show InChI InChI=1S/C22H16N2O4S2/c23-14-17-10-11-21(29(25)15-16-6-2-1-3-7-16)19(12-17)24-30(26,27)22-13-18-8-4-5-9-20(18)28-22/h1-13,24H,15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 50n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair